This document is part of the “SHEA neonatal intensive care unit (NICU) white paper series.” It is intended to provide practical, expert opinion, and/or evidence-based answers to frequently asked questions about CLABSI detection and prevention in the NICU. This document serves as a companion to the CDC Healthcare Infection Control Practices Advisory Committee (HICPAC) Guideline for Prevention of Infections in Neonatal Intensive Care Unit Patients.

Authors: Martha Muller, MD1 , Kristina A. Bryant, MD2 , Claudia Espinosa, MD, MSC3 , Jill A. Jones, MS, APRN, NNP-BC4 , Caroline Quach, MD, MSc, FRCPC5 , Jessica R. Rindels, MBA, BSN, RN, CIC6 , Dan L. Stewart, MD7 , Kenneth M. Zangwill, MD8 , Pablo J. Sánchez, MD9

1 Pediatric Infectious Disease, University of New Mexico School of Medicine and UNM Health Sciences, Albuquerque, NM
2 Pediatric Infectious Diseases, University of Louisville and Norton Children’s, Louisville, KY
3 Pediatric Infectious Diseases, University of South Florida Morsani College of Medicine, Tampa, FL
4 Nationwide Children’s Hospital, Columbus, Ohio
5 Departments of Microbiology, Infectious Diseases and Immunology and Pediatrics, University of Montreal, Clinical Department of Laboratory Medicine, CHU Sainte-Justine (QC, Canada) – ORCID: 0000-0002-1170-9475
6 Children’s Mercy Hospital, Kansas City, MO; ORCID 0000-0002-2428-8462
7 Norton Children’s Hospital and the University of Louisville School of Medicine, Louisville, KY
8 Division of Pediatric Infectious Diseases and Department of Infection Prevention and Control, Harbor-UCLA Medical Center, Torrance, CA – ORCID: 0000-0002-5026-4368
9 Department of Pediatrics, Divisions of Neonatology and Pediatric Infectious Diseases, Nationwide Children’s Hospital, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Center for Perinatal Research, The Ohio State University College of Medicine, Columbus, OH 43205; ORCID 0000-0003-2437-1247

Corresponding author: Kristina A. Bryant, MD, Pediatric Infectious Diseases, University of Louisville and Norton Children’s, Louisville, KY,

To read the guideline