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Innovation in Neonatology: Making Infusion Therapy Visible
Introduction:
Advancing neonatal care demands innovations that address both technological and clinical blind spots. In our recent Lancet Child & Adolescent Health reply, we highlight an often-overlooked dimension of neonatal safety: the need for true precision in intravenous infusion therapy. At ultra-low flow rates (<5 mL/h), even minimal deviations can have outsized consequences. Delays, hidden occlusions, or backflow may silently undermine stabilisation — even when state-of-the-art infusion pumps are in use.
To confront this challenge, we propose real-time infusion monitoring as a context-neutral innovation that brings visibility, precision, and equity to neonatal care. Making infusion therapy truly visible represents a crucial step forward, because precision medicine begins with understanding what actually reaches the infant.
Authors:
- Matheus van Rens, Neonatal Intensive Care Unit, Radboudumc Amalia Children’s Hospital, Nijmegen, Netherlands
- Robin van der Lee, Neonatal Intensive Care Unit, Infermi Hospital, Rimini, Italy
- Giovanni Barone, Neonatal Intensive Care Unit, Infermi Hospital, Rimini, Italy
- Fiammetta Piersigilli, Neonatal Intensive Care Unit, Louvain University, Saint Luc, 1200 Brussels, Belgium
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Enhancing neonatal vascular access: proposing a patient-centered framework based on 7-Rights
The 7-Rights Framework for Neonatal VA proposes a structured, right-based, patient-centered approach to optimizing VA precision and safety. By integrating evidence-based practice, ethical considerations, and multidisciplinary collaboration, this framework enhances VA safety and procedural success, reduces variability in clinical practice, and ultimately improves patient outcomes while prioritizing family involvement and well-being. The framework’s adaptability ensures that it can evolve alongside technological advances, new research findings, and ethical developments, making it applicable not only in neonatal settings but also in broader VA care.
Authors
Matheus F. P. T. van Rens1,2 ✉, Kevin Hugill2,3, Robin van der Lee1, Fiammetta Piersigilli4, Bernhard Schwaberger5, Silke Mader6 and Agnes van den Hoogen7
© The Author(s), under exclusive licence to the International Pediatric Research Foundation, Inc 20251 Neonatal Intensive Care Unit, Radboudumc Amalia Children’s Hospital, Nijmegen, The Netherlands.
2 Formerly of Neonatal Intensive Care Unit, Women’s Wellness and Research
Center, Doha, Qatar.
3 Independent Scholar, Cumbria, UK.
4 Neonatal Intensive Care Unit, Louvain University, Saint Luc, Brussels, Belgium.
5 Division of Neonatology, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
6 The European Foundation for the Care of Newborn Infants (EFCNI), München, Germany.
7 Division Woman and Baby Wilhelmina Children’s Hospital Utrecht, Utrecht University, Utrecht, The Netherlands.
✉email: Roland.vanRens@radboudumc.nl
Pediatric Research; https://doi.org/10.1038/s41390-025-04521-z -
CICC placement in a 480g baby
Dr. Christian Breschan, our expert , has send us a new tutorial!
Department of Anesthesia, Klinikum Klagenfurt, Klagenfurt, Austria
Active member of the NEVAT -
The Modern Role of Neonatal PICCs Subspecialty
This perspective review examines the evolving role of neonatal peripherally inserted central catheters (n-PICCs) as a distinct subspecialty within neonatal vascular access.
n-PICCs are indispensable for delivering long-term intravenous therapies in critically ill neonates.
The review explores ethical considerations, equitable access to vascular access technologies and prioritisation of patient safety in procedural training. The implementation of specialised vascular access teams, rather than an all-staff model, is advocated to enhance procedural success, reduce device-related complications and promote a culture of accountability.
Future directions include the development of smart catheter technologies, pseudo-tunnelling techniques and simulation-based education to advance and maintain clinical competency.Authors
Matheus Van Rens (Roland)1,Matthew Ostroff2, Mohammad A. A. Bayoumi3
1 Neonatal Intensive Care Unit, Radboud University Medical Center, Amalia Children’s Hospital, Nijmegen, the Netherlands
2 St. Joseph’s Regional Medical Center, Paterson, New Jersey, USA
3 Neonatal Intensive Care Unit, Women’s Wellness and Research Center, Hamad Medical Corporation, Doha, QatarCorrespondence: Mohammad A. A. Bayoumi (moh.abdelwahab@hotmail.com)
Nursing in Critical Care, 2025; 30:e70111
https://doi.org/10.1111/nicc.70111 -
The NAVIGATE project: A GloVANet–WoCoVA position statement on the nomenclature for vascular access devices
Recognizing the necessity for standardized terminology, the Global Vascular Access Network (GloVANet), in collaboration with the World Congress of Vascular Access (WoCoVA), initiated the NAVIGATE project (NomenclAture Via Integrated Global Advancements in Terminology Efficiencies).
The outcome of this collaborative effort is a WoCoVA/GloVANet position statement, which provides standardized nomenclature for vascular access devices. The adoption of unified terminology brings several benefits, firstly, it ensures clarity, reproducibility, and comparability when reporting in clinical studies, and secondly, reduces ambiguous or imprecise terms in communication between healthcare professionals in clinical practice.
van-rens-et-al-2024-the-navigate-project-a-glovanet-wocova-position-statement-on-the-nomenclature-for-vascular-accessDownloadAuthors
Matheus (Roland) van Rens1, Robin van der Lee1,
Timothy R Spencer2, Ton van Boxtel3, Giovanni Barone4,
Alessandro Crocoli5, Fulvio Pinelli6, Mauro Pittiruti7, on behalf of the WoCoVA Foundation (World Conference on Vascular Access) and of the Global Vascular Access Network (GloVANet)1 Radboudumc Amalia Kinderziekenhuis, Nijmegen, Netherlands
2 Global Vascular Access, LLC, Scottsdale, AZ, USA
3 Infusion Innovations, Utrecht, Netherlands
4 Ospedale Infermi, Rimini, Italy
5 Ospedale Pediatrico Bambino Gesù, Rome, Italy
6 Careggi University Hospital, Florence, Italy
7 Catholic University Hospital, Rome, ItalyCorresponding author: Mauro Pittiruti, Catholic University Hospital, Largo Francesco Vito 1, Rome 00168, Italy.
Email: mauropittiruti@me.comThe Journal of Vascular Access 1–8
DOI://10.1177/1297298241291248248 journals.sagepub.com/home/jva -
EAPS 2024 – Presentations of our pre-congress course Neonatal and pediatric vascular access
This is the bundle with all the presentations given during our successful pre-congress of EAPS 2024 in Vienna.
Authors
Prof. F. Piersigilli – Belgium, Dr. Robin Van der Lee – The Netherlands, Dr. Vito D’andrea – Italy, Dr. GIovanni Barone – Italy, Mr. Roland van Rens – The Netherlands, Dr. Bernard Schwaberger –Austria
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Ultrasound for diagnosis of complications
Do you want to learn everything about complications of vascular access and how to prevent them by the use of ultrasound? Dr. B. De Bisschop,gave a very interesting presentation during the BVN/GBN vascular access workshop.
Authors
Dr Barbara De Bisschop, neonatologist, ZAS Belgium
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Ultrasound for central venous catheter and arterial access
The next presentation was given during the BNV/GBN Vascular ACCESS workshop in Brussels, by Dr Robin van der Lee, neonatologist in Radboud UMC Nijmegen, it was about Ultrasound for insertion of CVAD and IAC in neonates.
Authors
Dr Robin van der Lee, pediatrician – neonatologist, Amalia Children’s Hospital, Nijmegen, NL
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Physics and artefacts of ultrasound
During the BNV/GBN Vascular ACCESS workshop in Brussels, Dr Robin van der Lee, neonatologist in Radboud UMC Nijmegen, talked in his interesting presentation about physics and artefacts of Ultrasound.
Authors
Dr Robin van der Lee, pediatrician – neonatologist, Amalia Children’s Hospital, Nijmegen, NL
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Prevention of catheter related blood stream infections
During the BNV/GBN Vascular ACCESS workshop in Brussels, Brenda Van Delft, Advances Practice Nurse gave an interesting presentation on “What about infection prevention?”
In this presentation you can find definitions, bundles and strategies.Authors
Brenda Van Delft, Advances Practice Nurse, UZ Brussels
